基因调控课题组
1. Li Y, Wang H, Wang X, Jin W, Tan Y, Fang H, Chen S, Chen Z, Wang K. Genome-wide studies identify a novel interplay between AML1 and AML1/ETO in t(8;21) acute myeloid leukemia. Blood. 2016;127(2):233-242.
2. Wei S, Zhao M, Wang X, Li Y, Wang K. PU.1 controls the expression of long noncoding RNA HOTAIRM1 during granulocytic differentiation. Journal of Hematology & Oncology. 2016;9:44.
3. Wang X, Tan Y, Li Y, Li J, Jin W, Wang K. Repression of CDKN2C caused by PML/RARα binding promotes the proliferation and differentiation block in acute promyelocytic leukemia. Frontiers of Medicine. 2016;10(4):420-9.
4. Wei S, Wang K. Long noncoding RNAs: pivotal regulators in acute myeloid leukemia. Experimental Hematology & Oncology. 2016;5:30.
5. Yang X, Wang P, Liu J, Zhang H, Xi W, Jia X, Wang K. Coordinated regulation of the immunoproteasome subunits by PML/RARα and PU.1 in acute promyelocytic leukemia. Oncogene. 2014;33(21):2700-8.
6. Wang Y, Jin W, Jia X, Luo R, Tan Y, Zhu X, Yang X, Wang X, Wang K. Transcriptional repression of CDKN2D by PML/RARα contributes to the altered proliferation and differentiation block of acute promyelocytic leukemia cells. Cell Death and Disease. 2014; 5, e1431.
7. Zhang H, Fang H, Wang K. Reactive oxygen species in eradicating acute myeloid leukemic stem cells. Stem cell investigation. 2014; 1:13.
8. Zhang H, Mi J, Fang H, Wang Z, Wang C, Wu L, Zhang B, Yang W, Wang H, Minden M, Li J, Xi X, Chen S, Zhang J, Chen Z and Wang K. Preferential eradication of acute myelogenous leukemia stem cells by fenretinide. Proc Natl AcadSci USA. 2013;110(14):5606-11.
9. Luo R, Ye L, Tao C, Wang K. Simulation of E. coli gene regulation including overlapping cell cycles, growth, division, time delays and noise. PLoS One. 2013;8(4):e62380.
10. Jin W, Wu K, Li Y, Yang W, Zou B, Zhang F, Zhang J, Wang K. AML1-ETO targets and suppresses cathepsin G, a serine protease, which is able to degrade AML1-ETO in t(8;21) acute myeloid leukemia. Oncogene. 2013;32(15): 1978-87.
11. Qian M, Jin W, Zhu X, Jia X, Yang X, Du Y, Wang K* and Zhang J. Structurally differentiated cis-elements that interact with PU.1 are functionally distinguishable in acute promyelocytic leukemia. Journal of Hematology & Oncology. 2013;6:25. (*co-corresponding author)
12. Zhu X, Zhang H, Qian M, Zhao X, Yang W, Wang P, Zhang J and Wang K. The significance of low PU.1 expression in patients with acute promyelocytic leukemia. Journal of Hematology & Oncology. 2012;5:22.
13. Zou D, Yang X, Wang P, Zhu X, Yang W, Jia X, Zhang J and Wang K. Regulation of the hematopoietic cell kinase gene by PML/RARα and PU.1 in acute promyelocytic leukemia. Leukemia Res. 2012;36:219-223.
14. Shi J, Yang W, Chen M, Du Y, Zhang J and Wang K. AMD, an automated motif Discovery Tool Using Stepwise Refinement of Gapped Consensuses. PLoS One. 2011;6(9),e24576.
15. Fang H, Du Y, Xia L, Li J, Zhang J, Wang K. A Topology-Preserving Selection and Clustering Approach to Multi-Dimensional Biological Data. OMICS. 2011;15(7-8): 483-94.
16. Fang H, Jin W, Yang Y, Jin Y, Zhang J and Wang K. An organogenesis network-based comparative transcriptome analysis for understanding early human development in vivo and in vitro. BMC Systems Biology. 2011;5:108.
17. Wang K, Wang P, Shi J, Zhu X, He M, Jia X, Yang X, Qiu F, Jin W, Qian M, Fang H, Mi J, Yang X, Xiao H, Minden M, Du Y, Chen Z, and Zhang J. PML/RAR targets promoter regions containing PU.1 consensus and RARE half sites in acute promyelocytic leukemia. Cancer Cell. 2010;17(2):186-197.
18. Yan J, Wang K#, Dong L, Liu H, Chen W, Xi W, Ding Q, Kieffer N, Caen J, Chen S, Chen Z and Xi X. PML/RARα fusion protein transactivates the tissue factor promoter through a GAGC-containing element without direct DNA association. Proc Natl Acad Sci USA. 2010;107(8):3716-21. (# co-first author)